方法对比

	混合中心复合设计	响应面方法 (RSM)
领域	实验设计	实验设计
方法族	Process / pipeline	Hypothesis test
起源年份	1976	1951
提出者	K. G. Roquemore	George E. P. Box & K. B. Wilson
类型	Response surface experimental design	Second-order polynomial response surface model
开创性文献	Roquemore, K. G. (1976). Hybrid designs for quadratic response surfaces. Technometrics, 18(4), 419–423.	Box, G. E. P. & Wilson, K. B. (1951). On the experimental attainment of optimum conditions. Journal of the Royal Statistical Society, Series B, 13(1), 1–45.
别名	Hybrid CCD, HCCD, modified central composite design, hybrid RSM design	RSM, Central Composite Design, Box-Behnken Design, CCD
相关	3	7
摘要	Hybrid Central Composite Design (Hybrid CCD) is a class of response surface designs introduced by Roquemore (1976) that combines the structural properties of classical central composite designs with modified or reduced point configurations to achieve rotatability or near-rotatability with fewer experimental runs than a standard CCD, making it especially practical when the number of factors is three to six and experimental resources are limited.	Response Surface Methodology is a collection of statistical and mathematical techniques for building an empirical second-order polynomial model that relates a continuous response variable to two or more controllable input factors, and then locating the factor settings that optimize that response. The approach was introduced by George E. P. Box and K. B. Wilson in their landmark 1951 paper and has since become a cornerstone of process optimization across engineering, chemistry, food science, and pharmaceutics.