方法对比

	柔性参数生存模型（Royston-Parmar）	加速失效时间 (AFT) 模型
领域	生存分析	生存分析
方法族	Survival analysis	Survival analysis
起源年份	2002	1992
提出者	Royston, P. & Parmar, M.K.B.	Wei, L. J. (seminal review 1992); origins in parametric survival literature
类型	Parametric survival regression model	Parametric survival regression model
开创性文献	Royston, P. & Parmar, M.K.B. (2002). Flexible Parametric Proportional-Hazards and Proportional-Odds Models for Censored Survival Data, with Application to Prognostic Modelling and Estimation of Treatment Effects. Statistics in Medicine, 21(15), 2175–2197.	Wei, L. J. (1992). The Accelerated Failure Time Model: A Useful Alternative to the Cox Regression Model in Survival Analysis. Statistics in Medicine, 11(14–15), 1871–1879.
别名	flexible parametric model, restricted cubic spline survival model, stpm2, Esnek Parametrik Survival Modeli (Royston-Parmar)	AFT model, parametric survival regression, Hızlandırılmış Başarısızlık Zamanı Modeli (AFT)
相关	8	3
摘要	The Royston-Parmar model, introduced by Royston and Parmar in 2002, is a modern parametric approach to survival analysis that replaces the rigid distributional assumptions of classical models with a restricted cubic spline fitted to the log-cumulative-hazard scale. It combines the interpretability of a fully parametric model with the flexibility to capture non-standard hazard shapes, and it supports proportional-hazards, accelerated failure-time, and proportional-odds link functions.	The Accelerated Failure Time model is a parametric regression approach to survival analysis — formally reviewed and advocated by L. J. Wei in 1992 — in which covariates act as multiplicative factors that directly stretch or compress the time-to-event scale. Unlike the Cox proportional-hazards model, which models how covariates shift the hazard rate, AFT models express the covariate effect as an acceleration or deceleration of the time axis itself.