方法对比
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| 28关节疾病活动度评分 (DAS28)× | Routine Assessment of Patient Index Data 3 (RAPID3)× | |
|---|---|---|
| 领域 | 风湿病学 | 风湿病学 |
| 方法族 | Process / pipeline | Process / pipeline |
| 起源年份≠ | 1995 | 2008 |
| 提出者≠ | Prevoo et al. | Pincus et al. |
| 类型≠ | Clinician-rated | Patient-reported outcome (PRO) |
| 开创性文献≠ | Prevoo ML, Hart's AM, Van Houwelingen HC, et al. Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis & Rheumatism. 1995;38(1):44-48. DOI ↗ | Pincus T, Bergman MJ, Sokka T, Roth SH, Swearingen C, Yazici Y. Activity of rheumatoid arthritis is similar in patients seen in a primary care physician-based practice and in an academic rheumatology-based practice. Arthritis Care Research. 2008;59(9):1229-1236. link ↗ |
| 别名≠ | DAS28, DAS28-CRP, DAS28-ESR | RAPID3, RAPID-3 |
| 相关 | 3 | 3 |
| 摘要≠ | The DAS28 is a composite measure of rheumatoid arthritis (RA) disease activity, combining joint counts, inflammatory markers, and patient-reported global health. Developed in 1995 by Prevoo and colleagues, it has become the gold standard for monitoring RA activity in clinical trials and practice. It integrates objective clinical signs with laboratory and subjective assessment, providing a single numerical index of disease burden. | RAPID3 is a patient-reported outcome (PRO) measure of rheumatoid arthritis disease activity based on three simple self-report items: patient-counted swollen and tender joints and overall health assessment. Introduced by Pincus et al. in 2008, RAPID3 was designed for primary care and busy practices where joint examination is impractical or time-limited. Remarkably, RAPID3 correlates strongly with clinician-examined composite measures (DAS28, CDAI, SDAI) and predicts long-term radiographic progression equally well, making it a practical alternative for resource-limited settings and self-directed monitoring. |
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