方法对比

	簇随机多臂试验	整群随机对照试验
领域	实验设计	实验设计
方法族	Process / pipeline	Process / pipeline
起源年份	1990s–2000s (systematic formalization)	1978–1980s
提出者	Building on cluster randomization (Donner & Klar) and multi-arm trial methods developed in clinical and public health research	Cornfield (1978); systematised by Donner and colleagues (1980s)
类型	Experimental design	Experimental design
开创性文献	Donner, A., & Klar, N. (2000). Design and Analysis of Cluster Randomization Trials in Health Research. Arnold. ISBN: 978-0340691533	Donner, A., & Klar, N. (2000). Design and Analysis of Cluster Randomization Trials in Health Research. Arnold. ISBN: 978-0340652978
别名	multi-arm cluster RCT, cluster-randomized multi-group trial, multi-arm group-randomized trial, CRCT multi-arm	cluster RCT, group-randomized trial, community randomized trial, cluster-randomized experiment
相关	6	4
摘要	A cluster randomized multi-arm experiment assigns intact groups — such as schools, clinics, or villages — rather than individuals to three or more experimental conditions simultaneously. Randomization occurs at the cluster level to prevent contamination between arms, while the multi-arm structure allows simultaneous evaluation of several interventions against a common control or each other, improving efficiency over a series of two-arm studies.	A cluster randomized controlled trial (cluster RCT) is an experimental design in which intact social or organisational groups — such as schools, clinics, villages, or workplaces — are randomly assigned to treatment conditions rather than individual participants. Outcomes are still measured at the individual level, but the unit of randomization is the cluster. This design is essential when an intervention is delivered to whole groups, when there is a risk of contamination between participants in the same setting, or when individual randomization is logistically or ethically impractical.