方法对比
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| 贝叶斯Kaplan-Meier分析× | Cox比例风险模型× | |
|---|---|---|
| 领域 | 流行病学 | 流行病学 |
| 方法族 | Process / pipeline | Process / pipeline |
| 起源年份≠ | 1976 | 1972 |
| 提出者≠ | Susarla & Van Ryzin (Bayesian nonparametric survival estimation) | Sir David Roxbee Cox |
| 类型≠ | Bayesian nonparametric survival analysis | Semi-parametric regression model |
| 开创性文献≠ | Susarla, V., & Van Ryzin, J. (1976). Nonparametric Bayesian estimation of survival curves from incomplete observations. Journal of the American Statistical Association, 71(356), 897–902. DOI ↗ | Cox, D. R. (1972). Regression models and life-tables. Journal of the Royal Statistical Society: Series B (Methodological), 34(2), 187–202. DOI ↗ |
| 别名 | Bayesian survival curve estimation, Bayesian nonparametric survival analysis, Dirichlet process Kaplan-Meier, BKM | Cox regression, Cox PH model, proportional hazards model, CPH |
| 相关≠ | 4 | 5 |
| 摘要≠ | Bayesian Kaplan-Meier analysis extends the classical Kaplan-Meier estimator by placing a prior distribution over the survival function and updating it with observed time-to-event data to obtain a full posterior distribution for the survival curve. This approach, rooted in Susarla and Van Ryzin's 1976 Dirichlet-process framework, yields credible intervals rather than confidence intervals and enables coherent incorporation of prior clinical knowledge, making it particularly valuable in small-sample or early-phase clinical settings. | The Cox proportional hazards model is a semi-parametric regression method that estimates the effect of one or more covariates on the hazard — the instantaneous rate of an event such as death, relapse, or failure — while making no assumption about the shape of the baseline hazard function. Introduced by David Cox in 1972, it is the dominant tool for multivariable survival analysis in clinical and epidemiological research. |
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