方法对比

	贝叶斯实验设计	响应面方法 (RSM)
领域	实验设计	实验设计
方法族	Process / pipeline	Hypothesis test
起源年份	1956 (foundational); formalized 1970s–1990s	1951
提出者	Lindley (1956); Chaloner & Verdinelli (1995) landmark review	George E. P. Box & K. B. Wilson
类型	Bayesian optimal experimental design	Second-order polynomial response surface model
开创性文献	Chaloner, K., & Verdinelli, I. (1995). Bayesian Experimental Design: A Review. Statistical Science, 10(3), 273–304.	Box, G. E. P. & Wilson, K. B. (1951). On the experimental attainment of optimum conditions. Journal of the Royal Statistical Society, Series B, 13(1), 1–45.
别名	Bayesian DOE, Bayesian optimal design, Bayesian experimental design, BDE	RSM, Central Composite Design, Box-Behnken Design, CCD
相关	3	7
摘要	Bayesian design of experiments selects experimental runs by maximising a utility function — typically the expected information gain — computed over prior beliefs about model parameters. Unlike classical design, which optimizes algebraic criteria such as D-optimality under fixed assumptions, Bayesian DOE incorporates prior knowledge and uncertainty about the system, yielding designs that are optimal in expectation across all plausible parameter values.	Response Surface Methodology is a collection of statistical and mathematical techniques for building an empirical second-order polynomial model that relates a continuous response variable to two or more controllable input factors, and then locating the factor settings that optimize that response. The approach was introduced by George E. P. Box and K. B. Wilson in their landmark 1951 paper and has since become a cornerstone of process optimization across engineering, chemistry, food science, and pharmaceutics.