เปรียบเทียบวิธี
ดูวิธีที่เลือกเทียบกันแบบเคียงข้าง แถวที่ต่างกันจะถูกเน้นไว้
| การทดลองทางคลินิกแบบสุ่ม (RCT)× | การศึกษาแบบกลุ่ม (Cohort Study)× | |
|---|---|---|
| สาขาวิชา | ระบาดวิทยา | ระบาดวิทยา |
| ตระกูล | Process / pipeline | Process / pipeline |
| ปีกำเนิด≠ | 1948 (first rigorously conducted RCT — MRC streptomycin trial) | Mid-20th century (formal epidemiological design codified ~1950s) |
| ผู้ริเริ่ม≠ | Austin Bradford Hill; MRC Streptomycin Trial team | Doll & Hill (British Doctors Study, 1951); Snow (cholera, 1854) |
| ประเภท≠ | Interventional experimental study | Observational longitudinal study design |
| แหล่งต้นตำรับ≠ | Friedman, L. M., Furberg, C. D., DeMets, D. L., Reboussin, D. M., & Granger, C. B. (2015). Fundamentals of Clinical Trials (5th ed.). Springer. ISBN: 978-3319185385 | Rothman, K. J., Greenland, S., & Lash, T. L. (2008). Modern Epidemiology (3rd ed.). Lippincott Williams & Wilkins. ISBN: 978-0781755641 |
| ชื่อเรียกอื่น | RCT, randomized controlled trial, randomised controlled trial, clinical randomized trial | longitudinal study, follow-up study, panel study, incidence study |
| ที่เกี่ยวข้อง | 6 | 6 |
| สรุป≠ | A randomized clinical trial (RCT) is an experimental study design in which participants are randomly assigned to an intervention group or a control group, then followed prospectively to compare outcomes. Random allocation is the defining feature: it distributes known and unknown confounders across groups by chance, making the RCT the strongest individual study design for establishing causal efficacy of a treatment or intervention under controlled conditions. | A cohort study assembles a group of individuals who share a common starting point — typically freedom from the outcome of interest — and follows them over time to observe who develops the outcome. By comparing incidence rates between exposed and unexposed subgroups, researchers can estimate relative risk and absolute risk differences. Cohort studies are the gold-standard observational design for measuring disease incidence and establishing temporal relationships between exposure and outcome. |
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