เปรียบเทียบวิธี

	การทดลองแบบออกแบบสำหรับหลายการตอบสนอง	ระเบียบวิธีพื้นผิวการตอบสนอง (Response Surface Methodology - RSM)
สาขาวิชา	การออกแบบการทดลอง	การออกแบบการทดลอง
ตระกูล	Process / pipeline	Hypothesis test
ปีกำเนิด	1980 (desirability function formalization); DoE roots from Fisher, 1920s–1930s	1951
ผู้ริเริ่ม	Derringer & Suich (desirability function); Montgomery (systematic DoE integration)	George E. P. Box & K. B. Wilson
ประเภท	Experimental optimization methodology	Second-order polynomial response surface model
แหล่งต้นตำรับ	Derringer, G., & Suich, R. (1980). Simultaneous optimization of several response variables. Journal of Quality Technology, 12(4), 214–219.	Box, G. E. P. & Wilson, K. B. (1951). On the experimental attainment of optimum conditions. Journal of the Royal Statistical Society, Series B, 13(1), 1–45.
ชื่อเรียกอื่น	Multi-response DoE, Multiple-response optimization, Multi-objective DoE, MRDoE	RSM, Central Composite Design, Box-Behnken Design, CCD
ที่เกี่ยวข้อง	4	7
สรุป	Multi-response Design of Experiments (MRDoE) extends classical DoE to situations where several response variables must be optimized simultaneously. Rather than tuning factors for a single output, the experimenter fits separate regression or response-surface models for each response, then combines them — most often via Derringer and Suich's desirability function — into a single composite score that guides the search for factor settings satisfying all response targets at once.	Response Surface Methodology is a collection of statistical and mathematical techniques for building an empirical second-order polynomial model that relates a continuous response variable to two or more controllable input factors, and then locating the factor settings that optimize that response. The approach was introduced by George E. P. Box and K. B. Wilson in their landmark 1951 paper and has since become a cornerstone of process optimization across engineering, chemistry, food science, and pharmaceutics.