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Radiomică×Reconstrucție Iterativă CT×Modelarea cinetică PET×
DomeniuImagistică medicalăImagistică medicalăImagistică medicală
FamilieProcess / pipelineProcess / pipelineProcess / pipeline
Anul apariției201219741983
Autorul originalPhilippe LambinRichard GordonChristoph Patlak
TipMachine learning-based texture and morphology analysisAlgorithm for tomographic image reconstructionMathematical framework for tracer kinetics in PET imaging
Sursa seminalăLambin, P., Rios-Velazquez, E., Leijenaar, R., et al. (2012). Radiomics: extracting more information from medical images using advanced feature analysis. Nature Reviews Clinical Oncology, 9(12), 676-684. DOI ↗Gordon, R., Bender, R., Herman, G. T. (1974). Algebraic reconstruction techniques (ART) for three-dimensional electron microscopy and X-ray photography. Journal of Theoretical Biology, 29(3), 471-481. link ↗Patlak, C. S., Blasberg, R. G., Fenstermacher, J. D. (1983). Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data. Journal of Cerebral Blood Flow & Metabolism, 3(1), 1-7. DOI ↗
Denumiri alternativetexture analysis, radiomics analysis, quantitative imaging biomarkersMBIR, ASIR, IR-CT, statistical reconstructionPET pharmacokinetics, Dynamic PET, PET compartmental modeling
Înrudite555
RezumatRadiomics is a computational methodology that extracts large numbers of quantitative features from medical images (CT, MRI, PET) using automated image analysis and machine learning to discover imaging biomarkers associated with disease phenotype, prognosis, and treatment response. Developed by Lambin, Gillies, and colleagues in 2012, radiomics aims to decode the biology underlying visible imaging patterns, enabling personalized medicine through image-based phenotyping. It has emerged as a powerful tool in oncology for tumor characterization, prognosis prediction, and therapy response assessment.CT Iterative Reconstruction (IR) is a computational technique that reconstructs tomographic images from raw X-ray projection data by iteratively refining an estimate of tissue attenuation until it matches the measured projections. Developed from algebraic reconstruction techniques pioneered by Gordon in 1974, iterative reconstruction has revolutionized clinical CT by enabling high-quality images at reduced radiation dose. Variants such as Adaptive Statistical Iterative Reconstruction (ASIR) and Model-Based Iterative Reconstruction (MBIR) are now standard on modern CT scanners.PET kinetic modeling is a quantitative analysis technique that tracks the temporal behavior of radioactive tracers in tissue to extract physiological parameters such as blood flow, metabolic rate, and receptor density. Established by Patlak, Logan, and Gunn in the 1980s and 1990s, kinetic modeling transforms raw PET time-activity curves into interpretable biological measures. It is widely used in neurology, oncology, and cardiology to assess disease severity, treatment response, and regional tissue function.
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ScholarGateCompară metode: Radiomics · CT Iterative Reconstruction · PET Kinetic Modeling. Preluat la 2026-06-20 de pe https://scholargate.app/ro/compare