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Modelul comun pentru date longitudinale și date de tip timp-până-la-eveniment×Analiza Landmark pentru Supraviețuirea Condiționată și Predicția Dinamică×
DomeniuSupraviețuireSupraviețuire
FamilieSurvival analysisSurvival analysis
Anul apariției20041983
Autorul originalTsiatis, A.A. & Davidian, M.; Rizopoulos, D.Anderson, J. R., Cain, K. C. & Gelber, R. D.
TipSemiparametric regression modelConditional survival estimator
Sursa seminalăRizopoulos, D. (2012). Joint Models for Longitudinal and Time-to-Event Data. CRC Press. DOI ↗Anderson, J. R., Cain, K. C. & Gelber, R. D. (1983). Analysis of Survival by Tumor Response. Journal of Clinical Oncology, 1(11), 710–719. DOI ↗
Denumiri alternativejoint model, shared random effects model, longitudinal-survival joint model, Joint Model (Boylamsal + Sağkalım Birleşik Model)landmark method, dynamic prediction, conditional survival estimation, Landmark Analizi (Dinamik Tahmin)
Înrudite53
RezumatThe joint model for longitudinal and time-to-event data, formalised by Tsiatis and Davidian in 2004 and extended comprehensively by Rizopoulos in 2012, simultaneously estimates a mixed-effects model for repeatedly measured biomarkers and a survival model for the time to an event, linking the two processes through shared random effects. It resolves two major problems that simpler approaches cannot handle: informative dropout from longitudinal studies and the endogeneity of time-varying biomarkers used as covariates in a Cox model.Landmark analysis, introduced by Anderson, Cain, and Gelber in 1983, estimates conditional survival probabilities for subjects who are still at risk at a pre-specified point in time — the landmark — rather than at study entry. It was developed explicitly to avoid immortal time bias that arises when subjects are grouped by an event (such as a treatment change or biomarker result) that can only occur if they remain event-free long enough to experience it.
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  3. PUBLISHED

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ScholarGateCompară metode: Joint Model for Longitudinal and Survival Data · Landmark Analysis. Preluat la 2026-06-18 de pe https://scholargate.app/ro/compare