Comparar métodos

	Modelo Paramétrico Flexível de Sobrevivência (Royston-Parmar)	Regressão de Riscos Proporcionais de Cox
Área	Análise de sobrevivência	Análise de sobrevivência
Família	Survival analysis	Survival analysis
Ano de origem	2002	1972
Autor original	Royston, P. & Parmar, M.K.B.	Cox, D. R.
Tipo	Parametric survival regression model	Semi-parametric hazard regression model
Fonte seminal	Royston, P. & Parmar, M.K.B. (2002). Flexible Parametric Proportional-Hazards and Proportional-Odds Models for Censored Survival Data, with Application to Prognostic Modelling and Estimation of Treatment Effects. Statistics in Medicine, 21(15), 2175–2197.	Cox, D. R. (1972). Regression Models and Life-Tables. Journal of the Royal Statistical Society: Series B, 34(2), 187–202.
Outros nomes	flexible parametric model, restricted cubic spline survival model, stpm2, Esnek Parametrik Survival Modeli (Royston-Parmar)	cox ph model, proportional hazards model, cox ph regression, Cox Orantılı Tehlikeler Regresyonu
Relacionados	8	3
Resumo	The Royston-Parmar model, introduced by Royston and Parmar in 2002, is a modern parametric approach to survival analysis that replaces the rigid distributional assumptions of classical models with a restricted cubic spline fitted to the log-cumulative-hazard scale. It combines the interpretability of a fully parametric model with the flexibility to capture non-standard hazard shapes, and it supports proportional-hazards, accelerated failure-time, and proportional-odds link functions.	Cox proportional hazards regression, introduced by D. R. Cox in 1972, is a semi-parametric model that estimates how one or more covariates affect the hazard — the instantaneous rate of experiencing an event — while leaving the baseline hazard function unspecified. It is the standard multivariable method in survival analysis and produces hazard ratios that quantify the relative risk associated with each predictor.