Sammenlign metoder
Gjennomgå de valgte metodene side om side; rader som avviker, er uthevet.
| Nelson-Aalen estimator for kumulativ hazard× | Cox proporsjonal hazardregresjon× | Delt fraktilitetsmodell for overlevelsesdata med klynger× | Kaplan-Meier overlevelsesestimator× | Log-rank-test for sammenligning av overlevelseskurver× | |
|---|---|---|---|---|---|
| Fagfelt | Overlevelsesanalyse | Overlevelsesanalyse | Overlevelsesanalyse | Overlevelsesanalyse | Overlevelsesanalyse |
| Familie | Survival analysis | Survival analysis | Survival analysis | Survival analysis | Survival analysis |
| Opprinnelsesår≠ | 1972 | 1972 | 1979 | 1958 | 1966 |
| Opphavsperson≠ | Wayne Nelson & Odd Aalen | Cox, D. R. | Vaupel, J.W., Manton, K.G. & Stallard, E. | Kaplan, E. L. & Meier, P. | Mantel, N. |
| Type≠ | Non-parametric cumulative hazard estimator | Semi-parametric hazard regression model | Random effects survival model | Non-parametric survival estimator | Non-parametric hypothesis test |
| Opprinnelig kilde≠ | Nelson, W. (1972). Theory and applications of hazard plotting for censored failure data. Technometrics, 14(4), 945–966. DOI ↗ | Cox, D. R. (1972). Regression Models and Life-Tables. Journal of the Royal Statistical Society: Series B, 34(2), 187–202. DOI ↗ | Vaupel, J.W., Manton, K.G. & Stallard, E. (1979). The Impact of Heterogeneity in Individual Frailty on the Dynamics of Mortality. Demography, 16(3), 439–454. DOI ↗ | Kaplan, E. L. & Meier, P. (1958). Nonparametric Estimation from Incomplete Observations. Journal of the American Statistical Association, 53(282), 457–481. DOI ↗ | Mantel, N. (1966). Evaluation of Survival Data and Two New Rank Order Statistics Arising in Its Consideration. Cancer Chemotherapy Reports, 50(3), 163–170. link ↗ |
| Alias≠ | Nelson-Aalen cumulative hazard, Aalen estimator, empirical cumulative hazard, Nelson-Aalen kümülatif hazard tahmincisi | cox ph model, proportional hazards model, cox ph regression, Cox Orantılı Tehlikeler Regresyonu | shared frailty model, random effects survival model, Frailty Modeli (Paylaşılan Kırılganlık) | product-limit estimator, km curve, kaplan-meier sağkalım analizi | Mantel log-rank test, Mantel-Cox test, log-rank sağkalım testi, Log-Rank Testi |
| Relaterte≠ | 5 | 3 | 3 | 2 | 2 |
| Sammendrag≠ | The Nelson-Aalen estimator is a non-parametric estimator of the cumulative hazard function from right-censored time-to-event data. Developed by Wayne Nelson for reliability hazard plotting in 1972 and placed on a rigorous counting-process foundation by Odd Aalen in 1978, it accumulates the ratio of observed events to the number at risk at each event time, providing the natural hazard-scale companion to the Kaplan-Meier survival curve. | Cox proportional hazards regression, introduced by D. R. Cox in 1972, is a semi-parametric model that estimates how one or more covariates affect the hazard — the instantaneous rate of experiencing an event — while leaving the baseline hazard function unspecified. It is the standard multivariable method in survival analysis and produces hazard ratios that quantify the relative risk associated with each predictor. | The shared frailty model, introduced by Vaupel, Manton, and Stallard in 1979, extends standard survival regression by incorporating a random effect — the 'frailty' — that captures unobserved heterogeneity among subjects or clusters. When survival outcomes are measured on individuals who share a common environment (patients in the same hospital, members of the same family, animals in the same litter), a frailty term accounts for the within-cluster dependence that ordinary Cox regression ignores. | The Kaplan-Meier estimator, introduced by Kaplan and Meier in 1958, is a non-parametric method that estimates the survival curve — the probability of remaining event-free over time — from right-censored time-to-event data. The log-rank test is the companion procedure used to compare survival curves between groups. | The log-rank test, developed by Nathan Mantel in 1966, is a non-parametric hypothesis test that compares the overall survival experience of two or more groups throughout the entire follow-up period. It is the standard companion to Kaplan-Meier curves and determines whether observed differences between curves are statistically meaningful. |
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