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Nelson-Aalen estimator for kumulativ hazard×Cox proporsjonal hazardregresjon×Delt fraktilitetsmodell for overlevelsesdata med klynger×Log-rank-test for sammenligning av overlevelseskurver×
FagfeltOverlevelsesanalyseOverlevelsesanalyseOverlevelsesanalyseOverlevelsesanalyse
FamilieSurvival analysisSurvival analysisSurvival analysisSurvival analysis
Opprinnelsesår1972197219791966
OpphavspersonWayne Nelson & Odd AalenCox, D. R.Vaupel, J.W., Manton, K.G. & Stallard, E.Mantel, N.
TypeNon-parametric cumulative hazard estimatorSemi-parametric hazard regression modelRandom effects survival modelNon-parametric hypothesis test
Opprinnelig kildeNelson, W. (1972). Theory and applications of hazard plotting for censored failure data. Technometrics, 14(4), 945–966. DOI ↗Cox, D. R. (1972). Regression Models and Life-Tables. Journal of the Royal Statistical Society: Series B, 34(2), 187–202. DOI ↗Vaupel, J.W., Manton, K.G. & Stallard, E. (1979). The Impact of Heterogeneity in Individual Frailty on the Dynamics of Mortality. Demography, 16(3), 439–454. DOI ↗Mantel, N. (1966). Evaluation of Survival Data and Two New Rank Order Statistics Arising in Its Consideration. Cancer Chemotherapy Reports, 50(3), 163–170. link ↗
AliasNelson-Aalen cumulative hazard, Aalen estimator, empirical cumulative hazard, Nelson-Aalen kümülatif hazard tahmincisicox ph model, proportional hazards model, cox ph regression, Cox Orantılı Tehlikeler Regresyonushared frailty model, random effects survival model, Frailty Modeli (Paylaşılan Kırılganlık)Mantel log-rank test, Mantel-Cox test, log-rank sağkalım testi, Log-Rank Testi
Relaterte5332
SammendragThe Nelson-Aalen estimator is a non-parametric estimator of the cumulative hazard function from right-censored time-to-event data. Developed by Wayne Nelson for reliability hazard plotting in 1972 and placed on a rigorous counting-process foundation by Odd Aalen in 1978, it accumulates the ratio of observed events to the number at risk at each event time, providing the natural hazard-scale companion to the Kaplan-Meier survival curve.Cox proportional hazards regression, introduced by D. R. Cox in 1972, is a semi-parametric model that estimates how one or more covariates affect the hazard — the instantaneous rate of experiencing an event — while leaving the baseline hazard function unspecified. It is the standard multivariable method in survival analysis and produces hazard ratios that quantify the relative risk associated with each predictor.The shared frailty model, introduced by Vaupel, Manton, and Stallard in 1979, extends standard survival regression by incorporating a random effect — the 'frailty' — that captures unobserved heterogeneity among subjects or clusters. When survival outcomes are measured on individuals who share a common environment (patients in the same hospital, members of the same family, animals in the same litter), a frailty term accounts for the within-cluster dependence that ordinary Cox regression ignores.The log-rank test, developed by Nathan Mantel in 1966, is a non-parametric hypothesis test that compares the overall survival experience of two or more groups throughout the entire follow-up period. It is the standard companion to Kaplan-Meier curves and determines whether observed differences between curves are statistically meaningful.
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ScholarGateSammenlign metoder: Nelson-Aalen Estimator · Cox Regression · Frailty Model · Log-Rank Test. Hentet 2026-06-19 fra https://scholargate.app/no/compare