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Risico-gecorrigeerde diagnostische nauwkeurigheidsstudie×Evaluatie van screeningsinstrumenten×
VakgebiedEpidemiologieEpidemiologie
FamilieProcess / pipelineProcess / pipeline
Jaar van ontstaanConceptual roots 1980s–1990s; covariate-adjusted ROC formally introduced 20091968 (Wilson-Jungner principles); statistical framework developed 1970s–2000s
GrondleggerMargaret Pepe and colleagues; covariate-adjusted ROC formalized by Janes & Pepe (2009)Wilson & Jungner (WHO criteria, 1968); foundational work by Pepe, Altman, and others in statistical test evaluation
TypeObservational clinical study design with covariate adjustmentObservational diagnostic / epidemiological evaluation design
Oorspronkelijke bronPepe, M. S. (2003). The Statistical Evaluation of Medical Tests for Classification and Prediction. Oxford University Press. ISBN: 978-0198509844Wilson, J. M. G., & Jungner, G. (1968). Principles and Practice of Screening for Disease. World Health Organization. Public Health Papers No. 34. link ↗
Aliassencase-mix-adjusted diagnostic accuracy, stratified diagnostic accuracy study, covariate-adjusted diagnostic accuracy, risk-stratified DTA studyscreening study, screening performance evaluation, screening accuracy assessment, STE
Verwant66
SamenvattingA risk-adjusted diagnostic accuracy study evaluates how well an index test identifies a target condition while explicitly accounting for patient-level risk factors that influence either disease prevalence or test performance. By adjusting for case-mix, it yields accuracy estimates — sensitivity, specificity, and AUC — that are not confounded by the composition of the study sample, enabling fairer comparisons across populations and clinical settings.Screening test evaluation is a systematic epidemiological approach for assessing whether a test or program can accurately and cost-effectively identify individuals with a condition before symptoms appear. It quantifies diagnostic performance metrics — sensitivity, specificity, predictive values, and the ROC curve — and evaluates whether a screening program meets established public health criteria for adoption and harm-benefit balance.
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ScholarGateMethoden vergelijken: Risk-adjusted diagnostic accuracy study · Screening Test Evaluation. Geraadpleegd op 2026-06-17 via https://scholargate.app/nl/compare