Methoden vergelijken

	Meta-analytische analyse van concurrerende risico's	Cox Proportional Hazards
Vakgebied	Epidemiologie	Epidemiologie
Familie	Process / pipeline	Process / pipeline
Jaar van ontstaan	2000s–2010s (formalized as a pooled approach)	1972
Grondlegger	Based on Fine & Gray (1999) competing risks framework; meta-analytic synthesis methods established through methodological literature (mid-2000s onward)	Sir David Roxbee Cox
Type	Systematic review / meta-analysis	Semi-parametric regression model
Oorspronkelijke bron	Riley, R. D., Hayden, J. A., Steyerberg, E. W., et al. (2013). Prognosis Research Strategy (PROGRESS) 2: Prognostic Factor Research. PLOS Medicine, 10(2), e1001380.	Cox, D. R. (1972). Regression models and life-tables. Journal of the Royal Statistical Society: Series B (Methodological), 34(2), 187–202.
Aliassen	meta-analysis of competing risks, pooled competing risks analysis, systematic review competing risks	Cox regression, Cox PH model, proportional hazards model, CPH
Verwant	5	5
Samenvatting	Meta-analytic competing risks analysis pools results from multiple primary studies that each used a competing risks framework, allowing summary estimates of cause-specific or subdistribution hazard ratios and cumulative incidence functions. Because standard meta-analytic methods may misrepresent competing events, specialized pooling strategies are required that respect the subdistribution hazard structure introduced by Fine and Gray and the distinction between cause-specific and all-cause hazard models.	The Cox proportional hazards model is a semi-parametric regression method that estimates the effect of one or more covariates on the hazard — the instantaneous rate of an event such as death, relapse, or failure — while making no assumption about the shape of the baseline hazard function. Introduced by David Cox in 1972, it is the dominant tool for multivariable survival analysis in clinical and epidemiological research.