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분야화학화학
계열Process / pipelineProcess / pipeline
기원 연도19691956
창시자Elias James CoreyRudolph A. Marcus
유형Strategic planning methodologyMechanistic framework
원전Corey, E. J., & Cheng, X. M. (1991). The Logic of Chemical Synthesis. John Wiley & Sons. ISBN: 978-0471096092Marcus, R. A. (1956). On the theory of oxidation-reduction reactions involving electron transfer. I. The Journal of Chemical Physics, 24(5), 966–978. DOI ↗
별칭retrosynthesis, retrosynthetic analysis, synthetic route designredox mechanism, electron transfer mechanism, oxidation-reduction
관련33
요약Synthesis route planning, grounded in retrosynthetic analysis, is a strategic approach to designing efficient chemical syntheses. Formalized by Elias James Corey in the 1960s (earning him the Nobel Prize in 1990), this methodology systematically deconstructs target molecules into simpler precursors and starting materials, enabling chemists to discover logical, economical, and practical synthesis routes.Redox reaction mechanism analysis is the systematic study of electron transfer pathways in oxidation-reduction reactions. Formalized by Rudolph Marcus in the 1950s (earning him the Nobel Prize in 1992), this framework explains how electrons move between reactants, what factors control reaction rates, and how electronic and geometric factors influence the ease of electron transfer.
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