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위험 조정 사례 시리즈×진단 정확도 연구 설계×
분야역학임상연구
계열Process / pipelineProcess / pipeline
기원 연도1990s–2000s2003-2015
창시자Copeland, Jones & Walters (POSSUM score, 1991); broader risk-adjustment methodology developed across surgical and critical care audit literatureBossuyt, Reitsma, and STARD group (2003); clinical epidemiology pioneers
유형Observational study design with statistical risk correctionResearch Design
원전Copeland, G. P., Jones, D., & Walters, M. (1991). POSSUM: a scoring system for surgical audit. British Journal of Surgery, 78(3), 355–360. DOI ↗Bossuyt, P. M., Reitsma, J. B., Bruns, D. E., Gatsonis, C. A., Glasziou, P. P., Irwig, L. M., ... & de Vet, H. C. (2003). Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative. Annals of Internal Medicine, 138(1), 40–44. DOI ↗
별칭risk-stratified case series, adjusted case series, risk-corrected case seriesdiagnostic accuracy study, test accuracy, STARD, diagnostic evaluation
관련52
요약A risk-adjusted case series is an observational study design that reports outcomes for a consecutive or defined group of patients undergoing the same procedure or sharing a condition, while statistically correcting for differences in patient-level baseline risk. Rather than presenting raw complication or mortality rates, it compares observed outcomes against expected rates derived from a validated scoring model (e.g., POSSUM, APACHE, ASA grade), enabling fairer evaluation of clinical performance across institutions or over time.A diagnostic accuracy study evaluates how well a new diagnostic test (or biomarker, imaging modality, clinical assessment) detects the presence or absence of disease compared to a reference standard (gold standard). Standardized since 2003 by the STARD (Standards for Reporting of Diagnostic Accuracy Studies) initiative, diagnostic accuracy studies are fundamental to clinical medicine, determining whether and how new tests can improve patient diagnosis and treatment.
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