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위험 조정 사례-교차 설계×위험 조정 코호트 연구×
분야역학역학
계열Process / pipelineProcess / pipeline
기원 연도1991 (base design); risk-adjustment extensions from mid-1990s onwardMid–late 20th century (risk-adjusted cohort designs systematized by 1970s–1990s)
창시자Malcolm Maclure (case-crossover base); extensions incorporating covariate risk adjustment developed in subsequent pharmacoepidemiology literatureEvolution of cohort study methodology; risk adjustment formalized through work of Rothman, Greenland, and others in epidemiology, 20th century
유형Observational analytic epidemiological designObservational epidemiological study design with statistical confounding control
원전Maclure, M. (1991). The case-crossover design: a method for studying transient effects on the risk of acute events. American Journal of Epidemiology, 133(2), 144–153. DOI ↗Rothman, K. J., Greenland, S., & Lash, T. L. (2008). Modern Epidemiology (3rd ed.). Lippincott Williams & Wilkins. ISBN: 978-0781755641
별칭adjusted case-crossover study, covariate-adjusted case-crossover, risk-controlled case-crossover, case-crossover with risk adjustmentadjusted cohort study, covariate-adjusted cohort, risk-controlled prospective study, propensity-adjusted cohort
관련44
요약The risk-adjusted case-crossover design is a self-matched epidemiological method that compares a person's exposure during a brief hazard window immediately preceding an acute event to their exposure during one or more control windows from the same individual, while formally accounting for time-varying or time-fixed covariates that could confound the exposure-event relationship. By using each case as their own control, stable individual-level confounders are automatically cancelled, while covariate adjustment handles residual time-varying risks.A risk-adjusted cohort study is an observational epidemiological design in which a defined group of individuals is followed over time to compare outcomes between exposed and unexposed subgroups, with statistical methods applied to control for measured confounders. Adjustment strategies — including multivariable regression, propensity score matching, inverse probability weighting, or standardization — are used to reduce bias and produce effect estimates that more closely approximate what would be observed in a randomized trial.
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ScholarGate방법 비교: Risk-adjusted case-crossover design · Risk-adjusted cohort study. 2026-06-19에 다음에서 검색함: https://scholargate.app/ko/compare