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실용적 진단 정확도 연구×코호트 연구×
분야역학역학
계열Process / pipelineProcess / pipeline
기원 연도2000s–2010s (formalized alongside STARD reporting guidelines)Mid-20th century (formal epidemiological design codified ~1950s)
창시자Evolved from STARD initiative (Bossuyt et al.) and pragmatic trial framework (Schwartz & Lellouch, 1967)Doll & Hill (British Doctors Study, 1951); Snow (cholera, 1854)
유형Observational diagnostic study designObservational longitudinal study design
원전Bossuyt, P. M., et al. (2015). STARD 2015: An Updated List of Essential Items for Reporting Diagnostic Accuracy Studies. BMJ, 351, h5527. DOI ↗Rothman, K. J., Greenland, S., & Lash, T. L. (2008). Modern Epidemiology (3rd ed.). Lippincott Williams & Wilkins. ISBN: 978-0781755641
별칭real-world diagnostic accuracy study, pragmatic DAS, routine-care diagnostic study, pragmatic test evaluationlongitudinal study, follow-up study, panel study, incidence study
관련66
요약A pragmatic diagnostic accuracy study evaluates how well a diagnostic test performs under real-world clinical conditions — not in idealized, tightly controlled settings. Conducted within routine care workflows, it measures sensitivity, specificity, predictive values, and likelihood ratios for an index test against a reference standard, yielding accuracy estimates directly applicable to clinical practice rather than laboratory benchmarks.A cohort study assembles a group of individuals who share a common starting point — typically freedom from the outcome of interest — and follows them over time to observe who develops the outcome. By comparing incidence rates between exposed and unexposed subgroups, researchers can estimate relative risk and absolute risk differences. Cohort studies are the gold-standard observational design for measuring disease incidence and establishing temporal relationships between exposure and outcome.
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