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환자 전반적 변화 인상 (PGIC)×임상적 전반적 인상 척도 (CGI)×
분야임상심리학임상심리학
계열Process / pipelineProcess / pipeline
기원 연도19761976
창시자William GuyWilliam Guy
유형Self-report single-item ratingClinician-rated assessment
원전Guy, W. (1976). ECDEU Assessment Manual for Psychopharmacology. Rockville, MD: National Institute of Mental Health, US Department of Health, Education, and Welfare. link ↗Guy, W. (1976). ECDEU Assessment Manual for Psychopharmacology. Rockville, MD: National Institute of Mental Health, US Department of Health, Education, and Welfare. link ↗
별칭PGIC, Patient Global Impression of Change ScaleCGI, CGI-S, CGI-I
관련44
요약The Patient Global Impression of Change is a single-item, seven-point rating scale asking patients to report their overall impression of change since treatment initiation. Originally published by William Guy in the ECDEU Assessment Manual in 1976, the PGIC has become a standard co-primary endpoint in clinical trials assessing treatment efficacy. The scale is endorsed by the FDA as a patient-reported outcome measure for demonstrating clinical benefit. Despite its simplicity, the PGIC captures patients' holistic perception of improvement—integrating symptom reduction, functional recovery, and subjective well-being.The Clinical Global Impressions Scale is a clinician-administered two-part assessment developed by William Guy in the ECDEU Assessment Manual (1976) to provide rapid, global ratings of illness severity and treatment response. Part 1 (CGI-Severity) rates current severity; Part 2 (CGI-Improvement) rates change since treatment initiation. The CGI is among the most widely used global outcome measures in psychiatric research and clinical practice, prized for its brevity, interpretability, and ability to capture clinician expertise and nuanced clinical judgment.
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