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메타분석 생존 분석×Kaplan-Meier 분석×
분야역학역학
계열Process / pipelineProcess / pipeline
기원 연도1990s–2000s (formalized ~1998)1958
창시자Parmar, Torri & Stewart (statistical framework); broader IPD tradition developed by the Early Breast Cancer Trialists' Collaborative GroupEdward L. Kaplan and Paul Meier
유형Quantitative synthesis / meta-analytic methodNonparametric survival estimator
원전Parmar, M. K. B., Torri, V., & Stewart, L. (1998). Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints. Statistics in Medicine, 17(24), 2815–2834. DOI ↗Kaplan, E. L., & Meier, P. (1958). Nonparametric estimation from incomplete observations. Journal of the American Statistical Association, 53(282), 457–481. DOI ↗
별칭meta-analysis of time-to-event data, pooled survival analysis, IPD survival meta-analysis, aggregate survival meta-analysisKM analysis, KM estimator, product-limit estimator, Kaplan-Meier curve
관련45
요약Meta-analytic survival analysis is a quantitative synthesis method that pools hazard ratios and related time-to-event statistics from multiple independent studies to produce a single, more precise estimate of a treatment or exposure effect on survival outcomes such as overall survival, disease-free survival, or time to relapse. It can operate on aggregate published data or on individual patient data (IPD) contributed directly by study investigators.Kaplan-Meier (KM) analysis is a nonparametric method for estimating the survival function from time-to-event data. Introduced by Kaplan and Meier in 1958, it produces the classic step-function survival curve that shows the probability of surviving beyond each observed event time, correctly accounting for censored observations — participants who left the study or had not yet experienced the event by the end of follow-up. It is one of the most widely used techniques in clinical and epidemiological research.
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