방법 비교
선택한 방법을 나란히 검토하세요. 서로 다른 행은 강조 표시됩니다.
| 등온 적정 열량측정법× | 전자 상자성 공명× | |
|---|---|---|
| 분야 | 분광학 | 분광학 |
| 계열 | Process / pipeline | Process / pipeline |
| 기원 연도≠ | 1989 | 1945 |
| 창시자≠ | Terrence Wiseman | Evgeny Zavoiskii |
| 유형≠ | Biophysical technique | Spectroscopic technique |
| 원전≠ | Wiseman, T., Williston, S., Brandts, J. F., & Lin, L. N. (1989). Rapid measurement of binding constants and heats of binding using a new titration calorimeter. Analytical Biochemistry, 179(1), 131-137. DOI ↗ | Zavoiskii, E. K. (1945). Paramagnetic relaxation of liquid solutions for perpendicular fields. Zhurnal Eksperimental'noi i Teoreticheskoi Fiziki, 15(6), 378-380. link ↗ |
| 별칭 | ITC, isothermal calorimetry, microcalorimetry | EPR spectroscopy, ESR, electron spin resonance |
| 관련 | 3 | 3 |
| 요약≠ | Isothermal Titration Calorimetry (ITC) is a thermodynamic technique that measures heat released or absorbed during biomolecular binding events at constant temperature. Developed by Wiseman and colleagues in 1989, ITC directly determines binding affinity (Kd), enthalpy (ΔH), and entropy (ΔS) in a single experiment, making it one of the most comprehensive methods for characterizing molecular interactions without requiring labels or immobilization. | Electron Paramagnetic Resonance (EPR), also called Electron Spin Resonance (ESR), is a spectroscopic technique that detects and characterizes unpaired electrons in molecules and materials. Discovered by Zavoiskii in 1945, EPR measures the absorption of microwave radiation by paramagnetic species in a magnetic field, providing information about electron spin states, local electronic environment, and molecular dynamics. |
| ScholarGate데이터셋 ↗ |
|
|