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혼합 생존 모형×생존 곡선 비교를 위한 로그-순위 검정×
분야생존분석생존분석
계열Survival analysisSurvival analysis
기원 연도19491966
창시자Boag, J. W.Mantel, N.
유형Parametric mixture survival modelNon-parametric hypothesis test
원전Boag, J. W. (1949). Maximum Likelihood Estimates of the Proportion of Patients Cured. Journal of the Royal Statistical Society B, 11(1), 15–53. link ↗Mantel, N. (1966). Evaluation of Survival Data and Two New Rank Order Statistics Arising in Its Consideration. Cancer Chemotherapy Reports, 50(3), 163–170. link ↗
별칭cure fraction model, cure rate model, bounded cumulative hazard model, İyileşme Modeli (Mixture Cure Model)Mantel log-rank test, Mantel-Cox test, log-rank sağkalım testi, Log-Rank Testi
관련22
요약The mixture cure model, first proposed by Boag in 1949 for cancer survival data, is a parametric survival model that explicitly accounts for a fraction of subjects who will never experience the event of interest — the so-called cured or immune fraction. It is the appropriate tool whenever the Kaplan-Meier curve levels off into a long, stable plateau rather than continuing to decline, indicating that a proportion of subjects are permanently event-free.The log-rank test, developed by Nathan Mantel in 1966, is a non-parametric hypothesis test that compares the overall survival experience of two or more groups throughout the entire follow-up period. It is the standard companion to Kaplan-Meier curves and determines whether observed differences between curves are statistically meaningful.
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