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교차 설계 실험실 실험×교차 무작위 대조 시험 (crossover RCT)×
분야실험설계실험설계
계열Process / pipelineProcess / pipeline
기원 연도Mid-20th century; consolidated 1980s–2000s1960s (Grizzle 1965 for statistical foundations); widely used in clinical research since the 1970s
창시자Established in pharmacological and behavioral research; Jones & Kenward formalized the frameworkEarly formalized by statisticians including Bradford Hill and colleagues in clinical trials; theoretical framework developed by Grizzle (1965) and later Senn (2002)
유형Within-subjects experimental designExperimental within-subject design
원전Jones, B., & Kenward, M. G. (2014). Design and Analysis of Cross-Over Trials (3rd ed.). CRC Press. ISBN: 978-1439861424Senn, S. (2002). Cross-over Trials in Clinical Research (2nd ed.). Wiley. ISBN: 978-0471496533
별칭within-subjects crossover lab study, repeated-measures crossover experiment, crossover controlled lab experiment, within-person laboratory crossover trialcrossover RCT, crossover trial, within-subject RCT, AB/BA crossover design
관련55
요약A crossover laboratory experiment is a within-subjects experimental design conducted in a controlled lab environment in which each participant receives two or more treatments sequentially, serving as their own control. By eliminating between-person variability from the error term, it yields high statistical power with relatively small samples. Treatment order is randomized or counterbalanced across participants to guard against order and carryover effects.A crossover randomized controlled trial (crossover RCT) is an experimental design in which each participant receives all study interventions in a randomized sequence, separated by a washout period. Because every participant serves as their own control, within-subject variability is eliminated from the treatment comparison, yielding greater statistical power per participant than a parallel-group RCT of equal size.
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