방법 비교

	중심합성계획	반응 표면 분석법 (RSM)
분야	실험설계	실험설계
계열	Process / pipeline	Hypothesis test
기원 연도	1951	1951
창시자	George E. P. Box and K. B. Wilson	George E. P. Box & K. B. Wilson
유형	Response surface experimental design	Second-order polynomial response surface model
원전	Box, G. E. P., & Wilson, K. B. (1951). On the experimental attainment of optimum conditions. Journal of the Royal Statistical Society: Series B, 13(1), 1–45.	Box, G. E. P. & Wilson, K. B. (1951). On the experimental attainment of optimum conditions. Journal of the Royal Statistical Society, Series B, 13(1), 1–45.
별칭	CCD, Box-Wilson design, central composite response surface design, rotatable central composite design	RSM, Central Composite Design, Box-Behnken Design, CCD
관련	3	7
요약	Central Composite Design (CCD) is a second-order response surface design that allows researchers to efficiently fit a full quadratic model relating multiple continuous input factors to one or more response variables. Introduced by Box and Wilson in 1951, it combines a factorial (or fractional factorial) core, axial (star) points, and center-point replicates into a single unified design, making it the most widely used design for process optimization in engineering, chemistry, and manufacturing.	Response Surface Methodology is a collection of statistical and mathematical techniques for building an empirical second-order polynomial model that relates a continuous response variable to two or more controllable input factors, and then locating the factor settings that optimize that response. The approach was introduced by George E. P. Box and K. B. Wilson in their landmark 1951 paper and has since become a cornerstone of process optimization across engineering, chemistry, food science, and pharmaceutics.