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Crohn's Disease Activity Index×궤양성 대장염의 메이요 점수×
분야소화기학소화기학
계열Process / pipelineProcess / pipeline
기원 연도19761987
창시자Best, W. R., Becktel, J. M., Singleton, J. W., and Kern, F.Schroeder, K. W., Tremaine, W. J., and Ilstrup, D. M.
유형Clinician-ratedClinician-rated
원전Best, W. R., Becktel, J. M., Singleton, J. W., & Kern, F. (1976). Development of a Crohn's disease activity index. National Cooperative Crohn's Disease Study. Gastroenterology, 70(3), 439–444. DOI ↗Schroeder, K. W., Tremaine, W. J., & Ilstrup, D. M. (1987). Coated oral 5-aminosalicylic acid therapy for mildly to moderately active ulcerative colitis. New England Journal of Medicine, 317(26), 1625–1629. DOI ↗
별칭CDAIMayo Clinic Score, UC Mayo Score
관련44
요약The Crohn's Disease Activity Index (CDAI) is a comprehensive, weighted index for assessing disease activity in Crohn's disease. Developed in 1976 by Best and colleagues for the National Cooperative Crohn's Disease Study, the CDAI integrates eight clinical and laboratory variables into a single score ranging from <150 (remission) to >450 (severe activity). Although more complex than symptom-based tools, the CDAI captures the multidimensional nature of Crohn's disease and remains the reference standard for severe disease assessment.The Mayo Score is a validated tool for assessing disease activity in ulcerative colitis, integrating clinical symptoms and endoscopic findings. Introduced by Schroeder and colleagues in 1987, it has become the reference standard for UC activity assessment in clinical trials and practice. The score combines stool frequency, rectal bleeding, overall physician global assessment, and endoscopic subscore into a single 0–12 scale.
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