手法を比較

	空間的反事実影響評価（SCIE）	因果推論のための操作変数（IV）法
分野	因果推論	医療経済学
系統	Regression model	Process / pipeline
提唱年	2010s	1990s (modern applications)
提唱者	Cerqua, Pellegrini, and regional-science scholars building on counterfactual econometrics	Angrist & Pischke (applied econometrics); rooted in econometric theory
種類	Quasi-experimental / causal inference	Method
原典	Cerqua, A., & Pellegrini, G. (2014). Do subsidies to private capital boost firms' growth? A multiple regression discontinuity design approach. Journal of Public Economics, 109, 114-126.	Angrist, J. D., & Pischke, J. S. (2009). Mostly Harmless Econometrics: An Empiricist's Companion. Princeton: Princeton University Press.
別名	SCIE, spatial CIE, place-based counterfactual evaluation, regional counterfactual analysis	IV, two-stage least squares, TSLS, causal estimation
関連	5	3
概要	Spatial Counterfactual Impact Evaluation (SCIE) is a family of quasi-experimental methods that estimate the causal effect of geographically targeted policies — such as EU Cohesion Funds, enterprise zones, or place-based subsidies — by constructing a spatial counterfactual: what outcomes the treated region would have experienced without the intervention, inferred from comparable untreated regions or from discontinuities at policy boundaries.	Instrumental variables (IV) is an econometric method to estimate causal effects when treatment or exposure is not randomly assigned and confounding is severe or unmeasured. IV relies on a third variable (instrument) that influences treatment but does not directly affect the outcome, allowing researchers to isolate the causal effect from the noise of confounding. Developed extensively in econometrics (Angrist & Pischke, 1990s–2000s), IV methods are increasingly used in health economics and health services research to leverage natural experiments and policy changes.