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| 後向き競合リスク分析× | Cox Proportional Hazards× | |
|---|---|---|
| 分野 | 疫学 | 疫学 |
| 系統 | Process / pipeline | Process / pipeline |
| 提唱年≠ | 1978 (cause-specific); 1999 (subdistribution/Fine-Gray) | 1972 |
| 提唱者≠ | Fine & Gray (subdistribution model); Prentice et al. (cause-specific framework) | Sir David Roxbee Cox |
| 種類≠ | Retrospective observational survival analysis | Semi-parametric regression model |
| 原典≠ | Fine, J. P., & Gray, R. J. (1999). A proportional hazards model for the subdistribution of a competing risk. Journal of the American Statistical Association, 94(446), 496–509. DOI ↗ | Cox, D. R. (1972). Regression models and life-tables. Journal of the Royal Statistical Society: Series B (Methodological), 34(2), 187–202. DOI ↗ |
| 別名 | retrospective CRA, competing risks survival analysis (retrospective), cause-specific hazard analysis (retrospective), subdistribution hazard analysis (retrospective) | Cox regression, Cox PH model, proportional hazards model, CPH |
| 関連≠ | 4 | 5 |
| 概要≠ | Retrospective competing risks analysis applies competing risks methodology to historical (already-collected) time-to-event data in which subjects can experience one of several mutually exclusive endpoints. It uses the cumulative incidence function and cause-specific or subdistribution hazard models to estimate the probability of each event type while accounting for the fact that occurrence of one event permanently precludes the others. Widely used in oncology, cardiology, and transplant medicine where administrative or registry records are the data source. | The Cox proportional hazards model is a semi-parametric regression method that estimates the effect of one or more covariates on the hazard — the instantaneous rate of an event such as death, relapse, or failure — while making no assumption about the shape of the baseline hazard function. Introduced by David Cox in 1972, it is the dominant tool for multivariable survival analysis in clinical and epidemiological research. |
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