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	Modellizzazione di Equazioni Strutturali	Statistica Spaziale Basata su Tratti (Tract-Based Spatial Statistics)
Campo	Statistica per la ricerca	Neuroimmagini
Famiglia	Process / pipeline	Process / pipeline
Anno di origine	1921	2006
Ideatore	Sewall Wright	Stephen M. Smith
Tipo	Method	Diffusion MRI white matter analysis pipeline
Fonte seminale	Jöreskog, K. G., & Sörbom, D. (1973). LISREL: A general computer program for estimating a linear structural equation system. Research Bulletin 73-5. University of Stockholm.	Smith, S. M., Jenkinson, M., Johansen-Berg, H., et al. (2006). Tract-based spatial statistics: voxelwise analysis of multi-subject diffusion data. NeuroImage, 31(4), 1487–1505.
Alias	SEM, path analysis, latent variable modeling, causal modeling	TBSS, white matter skeleton analysis
Correlati	3	3
Sintesi	Structural equation modeling (SEM) is a comprehensive statistical framework combining path analysis (Sewall Wright, 1921) and confirmatory factor analysis to test complex causal models linking observed and latent variables. Formalized by Jöreskog (1973) with LISREL software, SEM enables simultaneous estimation of measurement relationships (how variables measure latent constructs) and structural relationships (how constructs influence outcomes), making it powerful for theory testing in psychology, epidemiology, organizational research, and health sciences where complex mediation, moderation, and latent processes require integrated analysis.	Tract-Based Spatial Statistics (TBSS) is a voxel-wise analysis method for detecting group differences in white matter microstructure from diffusion MRI data. Published by Stephen M. Smith and colleagues in 2006, TBSS addresses registration and multiple comparison problems inherent in voxel-wise analysis by projecting individual FA maps onto a white matter skeleton derived from a population template.