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| Analisi Sequenziale (Disegno Sequenziale di Gruppo)× | Analisi della potenza bayesiana (Assurance)× | |
|---|---|---|
| Campo | Statistica | Statistica |
| Famiglia | Hypothesis test | Hypothesis test |
| Anno di origine≠ | 1977 | 1986 |
| Ideatore≠ | P. C. O'Brien & T. R. Fleming; P. C. Pocock | Spiegelhalter & Freedman (1986); O'Hagan, Stevens & Campbell (2005) |
| Tipo≠ | Sequential / adaptive hypothesis test | Bayesian sample size determination |
| Fonte seminale≠ | O'Brien, P.C. & Fleming, T.R. (1979). A Multiple Testing Procedure for Clinical Trials. Biometrics, 35(3), 549–556. DOI ↗ | O'Hagan, A., Stevens, J.W. & Campbell, M.J. (2005). Assurance in Clinical Trial Design. Pharmaceutical Statistics, 4(3), 187–201. DOI ↗ |
| Alias | sequential testing, group sequential design, interim analysis, Sıralı Analiz (Sequential Testing / Group Sequential Design) | assurance, bayesian sample size determination, bayesian assurance, Bayesian Güç Analizi (Assurance / Bayesian Sample Size) |
| Correlati≠ | 5 | 3 |
| Sintesi≠ | Sequential analysis is a framework for conducting hypothesis tests with pre-planned interim looks at accumulating data, allowing a study to stop early for efficacy or futility while controlling the overall Type I error rate. The group sequential approach was formalised by Pocock (1977) and O'Brien and Fleming (1979), and remains the standard for confirmatory clinical trials and rigorous A/B experiments. | Bayesian power analysis — also called assurance — is a sample size determination method that replaces the frequentist notion of power with a probability-weighted average over a prior distribution on the effect size. First formalised by Spiegelhalter and Freedman (1986) and further developed by O'Hagan, Stevens and Campbell (2005), it answers the question: given our current uncertainty about the true effect, what sample size gives us a high overall probability of obtaining a statistically significant result? |
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