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	Esperimento Fattoriale Frazionato Adattivo	Disegno Centrale Composito
Campo	Disegno sperimentale	Disegno sperimentale
Famiglia	Process / pipeline	Process / pipeline
Anno di origine	1950s–1960s (classical FFD); adaptive extensions formalized in 1990s–2000s	1951
Ideatore	Box, Hunter, and collaborators (adaptive/sequential extension of classical fractional factorial work)	George E. P. Box and K. B. Wilson
Tipo	Experimental design strategy	Response surface experimental design
Fonte seminale	Box, G. E. P., Hunter, J. S., & Hunter, W. G. (2005). Statistics for Experimenters: Design, Innovation, and Discovery (2nd ed.). Wiley-Interscience. ISBN: 978-0471718130	Box, G. E. P., & Wilson, K. B. (1951). On the experimental attainment of optimum conditions. Journal of the Royal Statistical Society: Series B, 13(1), 1–45.
Alias	adaptive FFE, sequential fractional factorial design, adaptive screening design, adaptive factor screening	CCD, Box-Wilson design, central composite response surface design, rotatable central composite design
Correlati	2	3
Sintesi	An adaptive fractional factorial experiment combines the resource-efficiency of fractional factorial designs with a sequential, data-driven strategy for selecting which factors and interactions to investigate next. Rather than committing all experimental runs upfront, the researcher analyses results from an initial fraction and uses those findings to guide subsequent rounds of experimentation — augmenting, folding, or redirecting the design until the active factors and optimal settings are identified with sufficient precision.	Central Composite Design (CCD) is a second-order response surface design that allows researchers to efficiently fit a full quadratic model relating multiple continuous input factors to one or more response variables. Introduced by Box and Wilson in 1951, it combines a factorial (or fractional factorial) core, axial (star) points, and center-point replicates into a single unified design, making it the most widely used design for process optimization in engineering, chemistry, and manufacturing.