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| Meta-analitikus túlélés-elemzés× | Túlélemzési módszerek× | |
|---|---|---|
| Tudományterület≠ | Epidemiológia | Kutatási statisztika |
| Módszercsalád | Process / pipeline | Process / pipeline |
| Keletkezés éve≠ | 1990s–2000s (formalized ~1998) | 1958 |
| Megalkotó≠ | Parmar, Torri & Stewart (statistical framework); broader IPD tradition developed by the Early Breast Cancer Trialists' Collaborative Group | Edward L. Kaplan and Paul Meier |
| Típus≠ | Quantitative synthesis / meta-analytic method | Method |
| Alapmű≠ | Parmar, M. K. B., Torri, V., & Stewart, L. (1998). Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints. Statistics in Medicine, 17(24), 2815–2834. DOI ↗ | Kaplan, E. L., & Meier, P. (1958). Nonparametric estimation from incomplete observations. Journal of the American Statistical Association, 53(282), 457–481. DOI ↗ |
| Alternatív nevek≠ | meta-analysis of time-to-event data, pooled survival analysis, IPD survival meta-analysis, aggregate survival meta-analysis | Kaplan-Meier analysis, Cox regression, TTE analysis |
| Kapcsolódó≠ | 4 | 3 |
| Összefoglaló≠ | Meta-analytic survival analysis is a quantitative synthesis method that pools hazard ratios and related time-to-event statistics from multiple independent studies to produce a single, more precise estimate of a treatment or exposure effect on survival outcomes such as overall survival, disease-free survival, or time to relapse. It can operate on aggregate published data or on individual patient data (IPD) contributed directly by study investigators. | Survival analysis is a collection of statistical methods for modeling time from a defined starting point until an event of interest occurs (disease, recovery, death, equipment failure). Kaplan and Meier's nonparametric estimator (1958) and David Cox's proportional hazards model (1972) jointly enabled analysis of censored data—individuals whose event times are unknown because they left the study or were still event-free at follow-up. Indispensable in oncology, cardiology, infectious disease research, engineering reliability, and any field where time-to-event matters. |
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