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Analiza žarišne točke za uvjetni opstanak i dinamičko predviđanje×Zajednički model za longitudinalne podatke i podatke o vremenu do događaja×Nelson-Aalenov procjenitelj kumulativne opasnosti×
PodručjeAnaliza preživljavanjaAnaliza preživljavanjaAnaliza preživljavanja
ObiteljSurvival analysisSurvival analysisSurvival analysis
Godina nastanka198320041972
TvoracAnderson, J. R., Cain, K. C. & Gelber, R. D.Tsiatis, A.A. & Davidian, M.; Rizopoulos, D.Wayne Nelson & Odd Aalen
VrstaConditional survival estimatorSemiparametric regression modelNon-parametric cumulative hazard estimator
Temeljni izvorAnderson, J. R., Cain, K. C. & Gelber, R. D. (1983). Analysis of Survival by Tumor Response. Journal of Clinical Oncology, 1(11), 710–719. DOI ↗Rizopoulos, D. (2012). Joint Models for Longitudinal and Time-to-Event Data. CRC Press. DOI ↗Nelson, W. (1972). Theory and applications of hazard plotting for censored failure data. Technometrics, 14(4), 945–966. DOI ↗
Drugi nazivilandmark method, dynamic prediction, conditional survival estimation, Landmark Analizi (Dinamik Tahmin)joint model, shared random effects model, longitudinal-survival joint model, Joint Model (Boylamsal + Sağkalım Birleşik Model)Nelson-Aalen cumulative hazard, Aalen estimator, empirical cumulative hazard, Nelson-Aalen kümülatif hazard tahmincisi
Srodne355
SažetakLandmark analysis, introduced by Anderson, Cain, and Gelber in 1983, estimates conditional survival probabilities for subjects who are still at risk at a pre-specified point in time — the landmark — rather than at study entry. It was developed explicitly to avoid immortal time bias that arises when subjects are grouped by an event (such as a treatment change or biomarker result) that can only occur if they remain event-free long enough to experience it.The joint model for longitudinal and time-to-event data, formalised by Tsiatis and Davidian in 2004 and extended comprehensively by Rizopoulos in 2012, simultaneously estimates a mixed-effects model for repeatedly measured biomarkers and a survival model for the time to an event, linking the two processes through shared random effects. It resolves two major problems that simpler approaches cannot handle: informative dropout from longitudinal studies and the endogeneity of time-varying biomarkers used as covariates in a Cox model.The Nelson-Aalen estimator is a non-parametric estimator of the cumulative hazard function from right-censored time-to-event data. Developed by Wayne Nelson for reliability hazard plotting in 1972 and placed on a rigorous counting-process foundation by Odd Aalen in 1978, it accumulates the ratio of observed events to the number at risk at each event time, providing the natural hazard-scale companion to the Kaplan-Meier survival curve.
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ScholarGateUsporedite metode: Landmark Analysis · Joint Model for Longitudinal and Survival Data · Nelson-Aalen Estimator. Preuzeto 2026-06-19 s https://scholargate.app/hr/compare