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Landmark-analüüs tingimuslikuks elulemuseks ja dünaamiliseks ennustamiseks×Ühismudel pikisuunaliste ja sündmuseni kuluvate aegade andmestikule×Kaplan-Meieri elulemuse estimaator×
ValdkondElukestusanalüüsElukestusanalüüsElukestusanalüüs
PerekondSurvival analysisSurvival analysisSurvival analysis
Tekkeaasta198320041958
LoojaAnderson, J. R., Cain, K. C. & Gelber, R. D.Tsiatis, A.A. & Davidian, M.; Rizopoulos, D.Kaplan, E. L. & Meier, P.
TüüpConditional survival estimatorSemiparametric regression modelNon-parametric survival estimator
AlgallikasAnderson, J. R., Cain, K. C. & Gelber, R. D. (1983). Analysis of Survival by Tumor Response. Journal of Clinical Oncology, 1(11), 710–719. DOI ↗Rizopoulos, D. (2012). Joint Models for Longitudinal and Time-to-Event Data. CRC Press. DOI ↗Kaplan, E. L. & Meier, P. (1958). Nonparametric Estimation from Incomplete Observations. Journal of the American Statistical Association, 53(282), 457–481. DOI ↗
Rööpnimetusedlandmark method, dynamic prediction, conditional survival estimation, Landmark Analizi (Dinamik Tahmin)joint model, shared random effects model, longitudinal-survival joint model, Joint Model (Boylamsal + Sağkalım Birleşik Model)product-limit estimator, km curve, kaplan-meier sağkalım analizi
Seotud352
KokkuvõteLandmark analysis, introduced by Anderson, Cain, and Gelber in 1983, estimates conditional survival probabilities for subjects who are still at risk at a pre-specified point in time — the landmark — rather than at study entry. It was developed explicitly to avoid immortal time bias that arises when subjects are grouped by an event (such as a treatment change or biomarker result) that can only occur if they remain event-free long enough to experience it.The joint model for longitudinal and time-to-event data, formalised by Tsiatis and Davidian in 2004 and extended comprehensively by Rizopoulos in 2012, simultaneously estimates a mixed-effects model for repeatedly measured biomarkers and a survival model for the time to an event, linking the two processes through shared random effects. It resolves two major problems that simpler approaches cannot handle: informative dropout from longitudinal studies and the endogeneity of time-varying biomarkers used as covariates in a Cox model.The Kaplan-Meier estimator, introduced by Kaplan and Meier in 1958, is a non-parametric method that estimates the survival curve — the probability of remaining event-free over time — from right-censored time-to-event data. The log-rank test is the companion procedure used to compare survival curves between groups.
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ScholarGateVõrdle meetodeid: Landmark Analysis · Joint Model for Longitudinal and Survival Data · Kaplan-Meier. Loetud 2026-06-19 aadressilt https://scholargate.app/et/compare