Process / pipelineSimulation / optimization

Robust Microsimulation — Uncertainty-Integrated Individual-Level Simulation

Robust Microsimulation combines individual-level (micro) simulation with systematic uncertainty analysis — typically probabilistic sensitivity analysis — to generate outputs that are robust to parameter uncertainty, model structure assumptions, and input variability. It is widely used in health technology assessment, public policy, and social science to produce credible, decision-relevant predictions.

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Sources

  1. O'Brien, B. J., & Briggs, A. H. (2002). Analysis of uncertainty in health care cost-effectiveness studies: an introduction to statistical issues and methods. Statistical Methods in Medical Research, 11(6), 455-468. DOI: 10.1191/0962280202sm304ra
  2. Caro, J. J., Briggs, A. H., Siebert, U., & Burgess, K. A. (2012). Modeling good research practices — overview: a report of the ISPOR-SMDM Modeling Good Research Practices Task Force-1. Medical Decision Making, 32(5), 667-677. DOI: 10.1177/0272989X12454577

Related methods

ScholarGateRobust Microsimulation (Robust Microsimulation — Uncertainty-integrated individual-level simulation for policy and health analysis). Retrieved 2026-06-04 from https://scholargate.app/en/simulation/robust-microsimulation