Chronic Respiratory Disease Questionnaire

The CRQ is a 20-item, four-domain questionnaire developed by Guyatt and colleagues at McMaster University in 1987 to measure health-related quality of life specifically in patients with chronic respiratory disease, particularly chronic obstructive pulmonary disease and cystic fibrosis. Uniquely, the CRQ can be administered by interview or self-report, and its four domains (dyspnea, fatigue, emotional function, mastery) directly address the multidimensional burden of chronic respiratory disease. The CRQ has demonstrated exceptional responsiveness to pulmonary rehabilitation and other interventions, making it a preferred outcome measure in respiratory research and clinical practice.