Process / pipelinecognitive-screening

Telephone Interview for Cognitive Status

The Telephone Interview for Cognitive Status (TICS) is a telephone-administered cognitive screening instrument developed by Breitner and colleagues in the late 1980s and modified (TICS-m) to assess cognitive function in older adults via remote interview. Designed for epidemiological studies and clinical research where in-person assessment is impractical or resource-intensive, the TICS combines questions assessing orientation, attention, language, memory, and reasoning in a format suitable for administration by trained interviewers without specialized clinical equipment. It has become widely used in longitudinal cohort studies, clinical trials, and telemedicine settings for cognitive screening and monitoring.

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Sources

  1. Breitner, J. C., Folstein, M. F., & Murphy, E. A. (1989). Familial aggregation in Alzheimer dementia: comparison of risk estimates. Genet Epidemiol, 6(1), 35-45. DOI: 10.1002/gepi.1370060106
  2. Plassman, B. L., Welsh-Bohmer, K. A., Bigler, E. D., et al. (2007). Telephone assessment of cognitive function in older adults: the Adult Changes in Thought Study. Neuroepidemiology, 27(2), 92-100. DOI: 10.1159/000101908
  3. Breitner, J. C. S., Wyse, B. W., Anthony, J. C., et al. (1999). APOE-epsilon4 count predicts age when prevalence of AD increases, then declines: the Cache County Study. Neurology, 53(2), 321-331. DOI: 10.1212/WNL.53.2.321

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ScholarGateTICS (Telephone Interview for Cognitive Status). Retrieved 2026-06-04 from https://scholargate.app/en/gerontology/cognitive-telephone-screening