Process / pipelineEngineering methods

Optimization-Assisted Design of Experiments

Optimization-assisted design of experiments (OA-DoE) couples a structured experimental plan with a mathematical optimization engine to locate factor settings that simultaneously satisfy multiple response objectives. Rather than stopping at fitting a response surface model, the analyst applies desirability functions, genetic algorithms, or other optimizers to the fitted model to identify the global or near-global optimum across all responses of interest.

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Sources

  1. Derringer, G., & Suich, R. (1980). Simultaneous optimization of several response variables. Journal of Quality Technology, 12(4), 214–219. DOI: 10.1080/00224065.1980.11980968
  2. Myers, R. H., Montgomery, D. C., & Anderson-Cook, C. M. (2016). Response Surface Methodology: Process and Product Optimization Using Designed Experiments (4th ed.). Wiley. ISBN: 978-1118916018

Related methods

ScholarGateOptimization-assisted design of experiments (Optimization-Assisted Design of Experiments). Retrieved 2026-06-04 from https://scholargate.app/en/experimental-design/optimization-assisted-design-of-experiments