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Time-series pathway enrichment analysis/Evidence
Method evidence record

Time-series pathway enrichment analysis

Time-series pathway enrichment analysis identifies biological pathways whose coordinated gene activity changes significantly across ordered time points. Rather than treating each time point independently, the method models the temporal trajectory of gene expression within each pathway and tests whether entire biological programs — not just individual genes — are activated or suppressed in a time-dependent manner. It is widely used in developmental biology, drug response studies, and infection time courses.

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Source record

Citations copied verbatim from the method’s source record. No claim-level verification is inferred from them.

Time-Series Pathway Enrichment Analysis
Taxonomic method record · process-pipeline / bioinformatics
  • Ernst, J., Nau, G. J., & Bar-Joseph, Z. (2005). Clustering short time series gene expression data. Bioinformatics, 21(Suppl 1), i159–i168. · URL
  • Cheng, J., Tegge, A. N., & Bhatt, D. L. (2014). A method for identifying and interpreting time-series pathway activity changes from gene expression data. Bioinformatics, 30(21), 3147–3154. · URL
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Related methods

Generated from the method graph and shown as machine-suggested relations — no evidence claim is inferred.

Taxonomic bucketGene Set Enrichment Analysismachine-suggested · Relational suggestion, not evidence.Taxonomic bucketMulti-omics Pathway Enrichment Analysismachine-suggested · Relational suggestion, not evidence.Taxonomic bucketPathway Enrichment Analysismachine-suggested · Relational suggestion, not evidence.Taxonomic bucketRNA-seq Differential Expressionmachine-suggested · Relational suggestion, not evidence.Taxonomic bucketTime-series RNA-seq differential expressionmachine-suggested · Relational suggestion, not evidence.

Evidence status

Sources recorded, not reviewed

Bibliographic sources are present. Claim-level evidence review has not been performed.

Sources

2 recorded citations, copied from the method source record.

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