Time-series ChIP-seq peak calling
Time-series ChIP-seq peak calling extends standard chromatin immunoprecipitation sequencing analysis to samples collected at multiple time points. By identifying and comparing protein-DNA binding peaks across a temporal dimension, the method reveals how transcription factor occupancy, histone modifications, or chromatin remodeler binding evolve during biological processes such as differentiation, circadian cycles, or stimulus response.
Source record
Citations copied verbatim from the method’s source record. No claim-level verification is inferred from them.
- Landt, S. G., Marinov, G. K., Kundaje, A., Kheradpour, P., Pauli, F., Batzoglou, S., ... & Snyder, M. (2012). ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia. Genome Research, 22(9), 1813–1831. · DOI 10.1101/gr.136184.111
- Haiminen, N., Karlebach, G., Kharchenko, P. V., & Lähdesmäki, H. (2018). TimeChIP: time-series peak calling for ChIP-seq data. Bioinformatics, 34(24), 4161–4167. · URL
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