SERS
Surface-Enhanced Raman Spectroscopy (SERS) amplifies weak Raman signals by many orders of magnitude when analyte molecules are adsorbed on specially prepared metal (typically silver or gold) nanostructured surfaces. Discovered by Fleischmann, Hendra, and McQuillan in 1974, SERS enables detection of vibrational signatures of single molecules and ultra-trace contaminants, revolutionizing analytical chemistry and forensics.
Source record
Citations copied verbatim from the method’s source record. No claim-level verification is inferred from them.
- Fleischmann, M., Hendra, P. J., & McQuillan, A. J. (1974). Raman spectra of pyridine adsorbed at a silver electrode. Chemical Physics Letters, 26(2), 163-166. · DOI 10.1016/0009-2614(74)85388-1
- Jeanmaire, D. L., & Van Duyne, R. P. (1977). Surface raman spectroelectrochemistry: Part I. Heterocyclic, aromatic, and aliphatic amines adsorbed on the anodized silver electrode. Journal of Electroanalytical Chemistry, 84(1), 1-20. · DOI 10.1016/S0022-0728(77)80224-6
- Kneipp, K., Wang, Y., Kneipp, H., Perelman, L. T., Itzkan, I., Dasari, R. R., & Feld, M. S. (1997). Single molecule detection using surface-enhanced Raman scattering (SERS). Physical Review Letters, 78(9), 1667-1670. · DOI 10.1103/PhysRevLett.78.1667
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