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Risk-adjusted Cox Proportional Hazards/Evidence
Method evidence record

Risk-adjusted Cox Proportional Hazards

Risk-adjusted Cox proportional hazards regression extends the classical Cox (1972) survival model by simultaneously entering known confounders — age, sex, comorbidities, disease severity — into the model alongside the exposure of primary interest. This adjustment isolates the independent effect of the exposure on the hazard of an event, producing hazard ratios (HRs) that are not distorted by baseline differences between comparison groups. It is the most widely used method for multivariable survival analysis in clinical and epidemiological research.

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Citations copied verbatim from the method’s source record. No claim-level verification is inferred from them.

Risk-adjusted Cox Proportional Hazards Regression
Taxonomic method record · process-pipeline / epidemiology
  • Cox, D. R. (1972). Regression models and life-tables. Journal of the Royal Statistical Society: Series B (Methodological), 34(2), 187–202. · DOI 10.1111/j.2517-6161.1972.tb00899.x
  • Hosmer, D. W., Lemeshow, S., & May, S. (2008). Applied Survival Analysis: Regression Modeling of Time-to-Event Data (2nd ed.). Wiley. · ISBN 978-0471754992
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Related methods

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Taxonomic bucketCox proportional hazardsmachine-suggested · Relational suggestion, not evidence.See alsoKaplan-Meier Estimatormachine-suggested · Relational suggestion, not evidence.See alsoLog-Rank Testmachine-suggested · Relational suggestion, not evidence.Same method familyLogistic Regressionmachine-suggested · Relational suggestion, not evidence.Same method familyPropensity Score Matchingmachine-suggested · Relational suggestion, not evidence.

Evidence status

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Bibliographic sources are present. Claim-level evidence review has not been performed.

Sources

2 recorded citations, copied from the method source record.

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