Method evidence record

Adaptive Experiment

An adaptive experiment is an experimental design in which pre-specified rules allow the protocol to be modified — such as reallocating participants to better-performing arms, stopping early for efficacy or futility, or changing sample size — based on accumulating interim data, while maintaining statistical validity. Adaptive designs are widely used in clinical trials, behavioural economics, and online platform testing to improve efficiency and ethics without sacrificing inferential rigour.

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Adaptive Experimental Design

Taxonomic method record · process-pipeline / experimental-design

Chow, S. C., & Chang, M. (2008). Adaptive Design Methods in Clinical Trials. Chapman and Hall/CRC. · ISBN 978-1584886761
U.S. Food and Drug Administration. (2019). Adaptive Designs for Clinical Trials of Drugs and Biologics: Guidance for Industry. FDA. · URL

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Taxonomic bucketFactorial Experimentmachine-suggested · Relational suggestion, not evidence.Taxonomic bucketMulti-arm experimentmachine-suggested · Relational suggestion, not evidence.Used in the same domainRandomized Controlled Trialmachine-suggested · Relational suggestion, not evidence.Used in the same domainResponse Surface Methodologymachine-suggested · Relational suggestion, not evidence.See alsoSequential Analysismachine-suggested · Relational suggestion, not evidence.