Process / pipelineClinical / epidemiology
Retrospective Competing Risks Analysis
Retrospective competing risks analysis applies competing risks methodology to historical (already-collected) time-to-event data in which subjects can experience one of several mutually exclusive endpoints. It uses the cumulative incidence function and cause-specific or subdistribution hazard models to estimate the probability of each event type while accounting for the fact that occurrence of one event permanently precludes the others. Widely used in oncology, cardiology, and transplant medicine where administrative or registry records are the data source.
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Sources
- Fine, J. P., & Gray, R. J. (1999). A proportional hazards model for the subdistribution of a competing risk. Journal of the American Statistical Association, 94(446), 496–509. DOI: 10.1080/01621459.1999.10474144 ↗
- Prentice, R. L., Kalbfleisch, J. D., Peterson, A. V., Flournoy, N., Farewell, V. T., & Breslow, N. E. (1978). The analysis of failure time data in the presence of competing risks. Biometrics, 34(4), 541–554. DOI: 10.2307/2530374 ↗