Process / pipelineClinical / epidemiology
Multicenter Competing Risks Analysis
Multicenter competing risks analysis is a time-to-event method applied across multiple clinical centers to estimate the probability of a specific event of interest when other mutually exclusive events — competing risks — can preclude its occurrence. By pooling data from diverse sites, it achieves the sample sizes needed to model rare events and enables assessment of center-level variation in cumulative incidence and covariate effects.
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Sources
- Fine, J. P., & Gray, R. J. (1999). A proportional hazards model for the subdistribution of a competing risk. Journal of the American Statistical Association, 94(446), 496–509. DOI: 10.1080/01621459.1999.10474144 ↗
- Austin, P. C., Lee, D. S., & Fine, J. P. (2016). Introduction to the analysis of survival data in the presence of competing risks. Circulation, 133(6), 601–609. DOI: 10.1161/CIRCULATIONAHA.115.017719 ↗