Meta-analytic Kaplan-Meier Analysis — Pooled Survival Curve Synthesis

Meta-analytic Kaplan-Meier analysis synthesizes time-to-event data across multiple studies by pooling Kaplan-Meier survival estimates, either from reconstructed individual patient data or from summary statistics extracted from published curves. It produces a pooled survival function with confidence bands and enables formal heterogeneity testing across studies, offering higher statistical power and more generalizable survival estimates than any single study alone.