Process / pipelineBioinformatics / omics
Time-series Microbiome Diversity Analysis — Longitudinal Microbiome Diversity Analysis
Time-series microbiome diversity analysis tracks how the richness, evenness, and community composition of microbial communities change across multiple time points within the same subjects. By combining standard diversity metrics with longitudinal statistical models, it separates true temporal dynamics from inter-individual variation, identifying when and how perturbations such as diet changes, antibiotic treatment, or disease onset reshape the microbiome.
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Sources
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- Chen, Y., Lun, A. T. L., & Smyth, G. K. (2023). Differential abundance testing on single-cell data using quasi-likelihood methods. Genome Biology, 24(1), 188. link ↗