Methoden vergleichen

	Meta-analytische Analyse konkurrierender Risiken	Cox-Proportional-Hazards-Modell
Fachgebiet	Epidemiologie	Epidemiologie
Familie	Process / pipeline	Process / pipeline
Entstehungsjahr	2000s–2010s (formalized as a pooled approach)	1972
Urheber	Based on Fine & Gray (1999) competing risks framework; meta-analytic synthesis methods established through methodological literature (mid-2000s onward)	Sir David Roxbee Cox
Typ	Systematic review / meta-analysis	Semi-parametric regression model
Wegweisende Quelle	Riley, R. D., Hayden, J. A., Steyerberg, E. W., et al. (2013). Prognosis Research Strategy (PROGRESS) 2: Prognostic Factor Research. PLOS Medicine, 10(2), e1001380.	Cox, D. R. (1972). Regression models and life-tables. Journal of the Royal Statistical Society: Series B (Methodological), 34(2), 187–202.
Aliasnamen	meta-analysis of competing risks, pooled competing risks analysis, systematic review competing risks	Cox regression, Cox PH model, proportional hazards model, CPH
Verwandt	5	5
Zusammenfassung	Meta-analytic competing risks analysis pools results from multiple primary studies that each used a competing risks framework, allowing summary estimates of cause-specific or subdistribution hazard ratios and cumulative incidence functions. Because standard meta-analytic methods may misrepresent competing events, specialized pooling strategies are required that respect the subdistribution hazard structure introduced by Fine and Gray and the distinction between cause-specific and all-cause hazard models.	The Cox proportional hazards model is a semi-parametric regression method that estimates the effect of one or more covariates on the hazard — the instantaneous rate of an event such as death, relapse, or failure — while making no assumption about the shape of the baseline hazard function. Introduced by David Cox in 1972, it is the dominant tool for multivariable survival analysis in clinical and epidemiological research.