Methoden vergleichen

	Landmarkenanalyse für bedingte Überlebenszeiten und dynamische Vorhersagen	Nelson-Aalen-Schätzer für die kumulative Hazardfunktion
Fachgebiet	Überlebenszeitanalyse	Überlebenszeitanalyse
Familie	Survival analysis	Survival analysis
Entstehungsjahr	1983	1972
Urheber	Anderson, J. R., Cain, K. C. & Gelber, R. D.	Wayne Nelson & Odd Aalen
Typ	Conditional survival estimator	Non-parametric cumulative hazard estimator
Wegweisende Quelle	Anderson, J. R., Cain, K. C. & Gelber, R. D. (1983). Analysis of Survival by Tumor Response. Journal of Clinical Oncology, 1(11), 710–719.	Nelson, W. (1972). Theory and applications of hazard plotting for censored failure data. Technometrics, 14(4), 945–966.
Aliasnamen	landmark method, dynamic prediction, conditional survival estimation, Landmark Analizi (Dinamik Tahmin)	Nelson-Aalen cumulative hazard, Aalen estimator, empirical cumulative hazard, Nelson-Aalen kümülatif hazard tahmincisi
Verwandt	3	5
Zusammenfassung	Landmark analysis, introduced by Anderson, Cain, and Gelber in 1983, estimates conditional survival probabilities for subjects who are still at risk at a pre-specified point in time — the landmark — rather than at study entry. It was developed explicitly to avoid immortal time bias that arises when subjects are grouped by an event (such as a treatment change or biomarker result) that can only occur if they remain event-free long enough to experience it.	The Nelson-Aalen estimator is a non-parametric estimator of the cumulative hazard function from right-censored time-to-event data. Developed by Wayne Nelson for reliability hazard plotting in 1972 and placed on a rigorous counting-process foundation by Odd Aalen in 1978, it accumulates the ratio of observed events to the number at risk at each event time, providing the natural hazard-scale companion to the Kaplan-Meier survival curve.