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Koalescensteori

Koalescensteori er et probabilistisk rammeværk, der sporer den genealogiske historie af DNA-sekvenser bagud i tiden til deres seneste fælles stamfader. Denne metode, udviklet af John Kingman i 1982, udgør grundlaget for moderne populationsgenetik og gør det muligt for forskere at forstå demografiske begivenheder, estimere genetiske parametre og rekonstruere evolutionære historier ud fra moderne genetiske data.

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Kilder

  1. Kingman, J. F. C. (1982). The coalescent. Stochastic Processes and their Applications, 13(3), 235–248. DOI: 10.1016/0304-4149(82)90011-4
  2. Hudson, R. R. (1983). Properties of a neutral allele model with intragenic recombination. Theoretical Population Biology, 23(2), 183–201. DOI: 10.1016/0040-5809(83)90013-8
  3. Tajima, F. (1983). Evolutionary relationship of DNA sequences in finite populations. Genetics, 105(2), 437–460. DOI: 10.1093/genetics/105.2.437

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ScholarGate. (2026, June 3). Coalescent Theory of Genetic Ancestry. ScholarGate. https://scholargate.app/da/genetics/coalescent-theory

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ScholarGateCoalescent Theory (Coalescent Theory of Genetic Ancestry). Hentet 2026-06-15 fra https://scholargate.app/da/genetics/coalescent-theory · Datasæt: https://doi.org/10.5281/zenodo.20539026